Open AccessEpidemiological fectors and antibiotic susceptibility pattern of Salmonella spp
Author(s) -
Alpa Patel,
Nirmal Choraria
Publication year - 2021
Publication title -
ip international journal of medical microbiology and tropical diseases/ip international journal of medical microbiology and tropical diseases
Language(s) - English
Resource type - Journals
eISSN - 2581-4761
pISSN - 2581-4753
DOI - 10.18231/j.ijmmtd.2021.030
Subject(s) - nalidixic acid , salmonella , ciprofloxacin , ampicillin , microbiology and biotechnology , salmonella typhi , antimicrobial , typhoid fever , antibiotics , medicine , chloramphenicol , drug resistance , serotype , biology , bacteria , biochemistry , genetics , escherichia coli , gene
serovars Typhi and Paratyphi are known to cause enteric fever. Multidrug resistance in and has emerged as a cause of concern. To evaluate antimicrobial susceptibility patterns of Salmonella enteric serovar Typhi () and obtained from blood culture. : All isolates obtained from blood cultures of clinically suspected cases of enteric fever coming to microbiology laboratory, Nirmal hospital, from January 2015 to September 2017 were included in the study. Antimicrobial susceptibility patterns were determined using commercial antimicrobial disks chloramphenicol (30 μg), nalidixic acid (30 μg), ampicillin (10 μg), azithromycin (15 μg), cotrimoxazole (1.25/23.75 μg), ciprofloxacin (5 μg), and ceftriaxone (30 μg). Antimicrobial susceptibility testing was performed in accordance with the Clinical and Laboratory Standards Institute (CLSI) guidelines of respective year by KirbyBauer disc diffusion method. : Total 330 isolates of salmonella are there out of that 298 is . 32 are Salmonella para A, while 1 is of Salmonella para B. Enteric fever cases pick month are April, May, June and July. Sensitivity to first line drugs are > 80%, Nalidixic acid resistant Salmonella (NARS) are 79%, while Multi drug resistant (resistant to ampicillin, chloramphenicol and co-trimoxazole all three)Salmonella are 3%. : Periodic evaluation of antibiotic susceptibility pattern is necessary to see changing pattern of antibiotics. Evaluation of Nalidixic acid resistant Salmonella and periodic evaluation of multi drug resistant Salmonella is also important as emergence of MDR strain is observed in our study.