Open AccessCBC an indicator of development of retinopathy of prematurity
Author(s) -
Mohit Sharma,
Sachala Bhoi,
Sapna Devi,
Swikruti Jena
Publication year - 2022
Publication title -
indian journal of clinical and experimental opthalmology
Language(s) - English
Resource type - Journals
eISSN - 2395-1451
pISSN - 2395-1443
DOI - 10.18231/j.ijceo.2022.021
Subject(s) - retinopathy of prematurity , medicine , gestational age , birth weight , prospective cohort study , pediatrics , ophthalmology , gastroenterology , pregnancy , biology , genetics
To detect the association of complete blood count with retinopathy of prematurity. A prospective cohort study from May 2020-April 2021. Preterm infants having Gestation Age<34 weeks and birth weight <1750grams were included. All preterm babies CBC were done at birth. Ocular examination was done in all preterm babies after 3 weeks of birth and divided into two group one with ROP and other non-ROP.Chi-square test was used to analyze the difference between the ROP vs non-ROP group and p value <0.05 was taken as statistically significant. 150 preterm infants were screened for ROP out of which 47 were having ROP and 103 no any sign of ROP. The mean GA was 31 Weeks and mean birth weight was 1300 grams of ROP group. The mean Hb of ROP Group was 9.8g/dl as compared to Non-ROP Group having mean Hb-11.4g/dl (p<0.05) and MCH, PLT, MCV all were lower in ROP group as compared to non-ROP. CRP and leukocyte were higher in ROP Group as compared to non-ROP. As Hb and MCH plays an principal role in oxygen transport, low levels of these may cause increased vascular endothelial growth factor secretion from the hypoxic retina, leading to ROP. In our study we found that Retinopathy of prematurity infants were having lower Hb, MCH as compared to non-ROP Group.