Open AccessStudy of fasting & PP C- peptide & its correlation with HbA1c in T2 Diabetes mellitus in population of Uttarakhand
Author(s) -
Farah Ahsan,
Naeem Qureshi,
Sumera Samreen,
Sonali Kukreti
Publication year - 2022
Publication title -
international journal of clinical biochemistry and research
Language(s) - English
Resource type - Journals
eISSN - 2394-6377
pISSN - 2394-6369
DOI - 10.18231/j.ijcbr.2021.053
Subject(s) - c peptide , diabetes mellitus , peptide , endocrinology , medicine , insulin , population , etiology , biology , biochemistry , environmental health
We aimed to provide correlation of Fasting & PP C-peptide with HbA1C in patients of T2 Diabetes Mellitus. : 50 patients admitted in IPD of Medicine department in Shri Mahant Indresh Hospital from April-August 2021. Serum samples taken for fasting & PP C-peptide and HbA1C for patients of T2 Diabetes Mellitus and run on VITROS 5600/7600 which is based on dry chemistry. : We took 50 patients who were T2DM then we did fasting C peptide & PP C-peptide and HbA1c. Out of 50, 15 were females &35 were males. Out of 50, 45 patients had raised HbA1C maximum around 8-10. Mean & SD for fasting C-Peptide for males was 1.346±1.070 & for females 2.442±2.57. Mean & SD for Post prandiol C-Peptide for males was 4.208±5.020 & for females 2.993±2.130. It was significant for fasting C- Peptide with P value 0.0371 and non significant for PP C peptide with p value 0.3731. : Insulin secretion estimated by measurement of Fasting C-Peptide was either normal or raised in newly diagnosed T2DM subjects in my study indicating predominant role of insulin resistence in the etiology. Further research can explore the exact contribution of insulin resistence and insulin secretory defects in this area.