Open AccessPerioperative management of congenital hyperinsulinism (CHI)
Author(s) -
Parul Kaushik,
Nitin Hayaran,
Ishan Goel
Publication year - 2022
Publication title -
indian journal of clinical anaesthesia
Language(s) - English
Resource type - Journals
eISSN - 2394-4781
pISSN - 2394-4994
DOI - 10.18231/j.ijca.2022.051
Subject(s) - hypoglycemia , irritability , medicine , congenital hyperinsulinism , hyperinsulinism , vomiting , pediatrics , airway management , anesthesia , perioperative , nausea , neonatal hypoglycemia , insulin , airway , anxiety , pregnancy , psychiatry , insulin resistance , gestational diabetes , gestation , biology , genetics
Congenital hyperinsulinism (CHI) is one of the common causes of recurrent or persistent hypoglycemia. It is marked by islet cell dysfunction leading to insufficient suppression of insulin secretion in the presence of serious hypoglycemia. CHI is genetic in origin, where children present with symptoms of hypoglycemia like irritability, listlessness, nausea, vomiting, tachypnoea, seizure or with long-term sequelae such as developmental delay and focal neurologic deficits, thus making it a medical emergency. Surgical management becomes essential in most of the cases with challenging perioperative management. We successfully managed three such cases with favorable postoperative outcome.