Open AccessThe Molecular Mechanism and Drug Therapy of Heart Failure
Author(s) -
Yifan Su
Publication year - 2020
Publication title -
international journal of environmental sciences and development/international journal of environmental science and development
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.146
H-Index - 3
ISSN - 2010-0264
DOI - 10.18178/ijesd.2020.11.9.1290
Subject(s) - heart failure , drug , mechanism (biology) , medicine , selection (genetic algorithm) , intensive care medicine , disease , pharmacotherapy , drug discovery , bioinformatics , pharmacology , cardiology , computer science , biology , philosophy , epistemology , artificial intelligence
Heart failure (HF) is a complex clinical syndrome that results from left ventricular myocardial dysfunction and contributes to dyspnea, fatigue and fluid retention. It's essential to characterize disease progression and symptoms to optimize therapy selection. Also, understanding the mechanisms of HF to guide therapy selection is of vital importance. This review focuses on the demonstrating mechanisms of HF and points out the possible pathways involved in the process. Drug therapies of HF with different effects on specific targets are analyzed. Finally, we conclude the features of the now going drugs and depict the future perspectives of drug therapy of HF, including potential new targets and new drug therapies.