Open AccessPATHOGENIC PARTICULARITIES OF CARDIOVASCULAR CONTINUUM IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Author(s) -
Н. Т. Ватутин,
А. С. Смирнова,
Д. В. Борт,
Г. Г. Тарадин
Publication year - 2016
Publication title -
pulʹmonologiâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.126
H-Index - 6
eISSN - 2541-9617
pISSN - 0869-0189
DOI - 10.18093/0869-0189-2016-26-5-610-617
Subject(s) - copd , medicine , pulmonary disease , comorbidity , systemic inflammation , disease , endothelial dysfunction , oxidative stress , intensive care medicine , cardiology , inflammation
Chronic obstructive pulmonary disease (COPD) is currently considered as a systemic disease with multiple extrapulmonary manifestations which can negatively affect the prognosis. Cardiovascular abnormalities are main systemic manifestations of COPD. Cardiovascular diseases and COPD have common pathogenic features that include the systemic inflammatory response, oxidative stress and endothelial dysfunction. Main pathogenic mechanisms of this comorbidity were discussed in this review.