Open AccessAssociation between intracardiac hemodynamics and respiratory function in patients with coronary artery disease and respiratory comorbidity
Author(s) -
Е. Д. Баздырев,
О. М. Поликутина,
Н. А. Каличенко,
Ю. С. Слепынина,
Viktoria Pavlova,
О. Л. Барбараш
Publication year - 2016
Publication title -
pulʹmonologiâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.126
H-Index - 6
eISSN - 2541-9617
pISSN - 0869-0189
DOI - 10.18093/0869-0189-2016-26-3-328-335
Subject(s) - medicine , cardiology , coronary artery disease , spirometry , diastole , ventricle , comorbidity , ventilation (architecture) , obstructive lung disease , restrictive lung disease , doppler echocardiography , lung volumes , pulmonary function testing , lung , copd , blood pressure , asthma , mechanical engineering , engineering
The aim of this study was to investigate a relationship between the myocardial structure and function and respiratory parameters in patients with coronary artery disease (CAD) and respiratory disease. Methods. We performed spirometry, body plethysmography, lung diffusing capacity test and measured the left ventricle (LV) systolic and diastolic function in patients with CAD with or without respiratory diseases and ventilation disorders. Results. Patients with CAD (n = 662) participated in the study. The LV systolic dysfunction was found only in 60 patients (9.1%), while diastolic dysfunction was found in 387 patients with CAD (58.4%). Most patients with obstructive ventilation disorders had the systolic or diastolic LV dysfunction (40 patients (66.7%) and 197 patients (79.4%), respectively). Flow and volume lung function parameters and the lung diffusing capacity were associated with some echocardiographic and pulsed wave Doppler parameters. Conclusion . Comorbidity of CAD and lung obstructive disease was associated with more frequent systolic and diastolic LV dysfunction. The relationship between respiratory and cardiac parameters could indicate the cross impact that could deteriorate the course of both the diseases.