Open AccessClinical and functional featuresof respiratory heat exchange and cold airway hyperresponsiveness in patients with bronchial asthma and chronic polypous rhinosinusitis
Author(s) -
Э. В. Захарова
Publication year - 2008
Publication title -
pulʹmonologiâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.126
H-Index - 6
eISSN - 2541-9617
pISSN - 0869-0189
DOI - 10.18093/0869-0189-2008-0-6-59-62
Subject(s) - medicine , hyperventilation , asthma , airway , bronchial hyperresponsiveness , airway hyperresponsiveness , respiratory system , sinusitis , nasal polyps , anesthesia , gastroenterology , respiratory disease , immunology , lung
The aim of the study was to investigate airway conditioning function and cold hyperresponsiveness in patients with bronchial asthma (BA) and nasal polyps. One hundred and eleven asthma patients with or without chronic polypous rhinosinusitis (CPR) were examined. Respiratory heat exchange and cold airway hyperresponsiveness were assessed using thermometry of expired air during quiet breathing and isocapnic hyperventilation with cold air in comparison with a group of healthy persons. The conditioning nasal function was worsened in BA patients with CPRS. Disorders of nasal heat exchange led to decreased temperature of the exhaled air during quiet breathing and cold hyperventilation. These disorders were closely related to increased frequency and severity of cold airway hyperresponsiveness.