Open AccessPaths to improve diagnostic approach in chronic obstructive pulmonary disease with occupational etiology
Author(s) -
Н.А. Мокина,
V. A. Ageeva,
P. A. Kapishnikov
Publication year - 2008
Publication title -
pulʹmonologiâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.126
H-Index - 6
eISSN - 2541-9617
pISSN - 0869-0189
DOI - 10.18093/0869-0189-2008-0-4-62-66
Subject(s) - medicine , copd , spirometry , plethysmograph , etiology , chronic bronchitis , obstructive lung disease , occupational lung disease , lung , cardiology , respiratory system , hypersensitivity pneumonitis , radiology , asthma
The aim of this work was to study functional and diagnostic characteristics of COPD caused by exposure of occupational hazards (chronic dust related bronchitis) using conventional and novel diagnostic methods. The study involved 52 patients (28 males, 24 females) having a history of long-term exposure to low to moderate concentrations of silica dust at the workplace. Of them, 31 % were smokers, 11 % were ex-smokers quitting the smoking ≥ 1 year before, 58 % never smoked. All were diagnosed with moderate COPD. We analyzed findings of spirometry, body plethysmography, and amplitude-frequency characteristics of respiratory sounds using bronchophonography. The functional "image" of COPD caused by occupational hazards included mixed obstructive and restrictive disorders, lung emphysema signs in body plethysmography, significant obstructive disorders in bronchophonography in all the patients, bilateral diffuse and focal abnormalities of lung perfusion in multi-projectional perfusion scintigraphy, worse spirometric values in smokers compared with non-smokers.