Open AccessCell bronchopulmonary reactions in patients with pesticide accumulation and exacerbation of COPD
Author(s) -
S. I. Аrifkhanova,
Kamola Ubaydullaeva
Publication year - 2007
Publication title -
pulʹmonologiâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.126
H-Index - 6
eISSN - 2541-9617
pISSN - 0869-0189
DOI - 10.18093/0869-0189-2007-0-5-69-71
Subject(s) - exacerbation , copd , biocide , pesticide , medicine , stimulation , peripheral blood mononuclear cell , immunology , chemistry , pathology , biology , biochemistry , ecology , in vitro
Cell reactions of bronchopulmonary system in COPD exacerbation were investigated in BALF from 182 patients. Patients were divided into 2 groups: with or without pesticide accumulation. Smoking habit was also taken into consideration. We estimated biocide potential of AM using spontaneous and induced NST-test in 4 groups, calculated the stimulation index that revealed several patterns of cell reactions. Chronic excessive activation of AM by smoking, pesticides and/or other risk factors provided hyperresponsiveness of biocide systems of mononuclear monocytes.