Open AccessMathematical model of early dysfunction of cardiorespiratory system in early-stage COPD
Author(s) -
В. В. Гноевых
Publication year - 2007
Publication title -
pulʹmonologiâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.126
H-Index - 6
eISSN - 2541-9617
pISSN - 0869-0189
DOI - 10.18093/0869-0189-2007-0-2-63-67
Subject(s) - cardiorespiratory fitness , spirometry , medicine , copd , smoking history , cardiology , stage (stratigraphy) , respiratory system , physical therapy , asthma , paleontology , biology
Two hundred and ninety seven young medical students were divided in the study group (93 smokers) and the control group (204 non-smokers). Depending on smoking history and risk factors of COPD (GOLD, 2005), the smokers were divided into the risk-positive (32 % of the smokers) and risk-negative (68 % of the smokers) subgroups. Spirometry parameters, blood oxygenation and desaturation during a voluntary hold of breathing at the full inspiration were analyzed. As a result of mathematical modeling, we have proposed the respiratory gas index (RGI) that is an integral index of early cardiorespiratory dysfunction at the early-stage COPD. The lowest RGI was in the study group especially in smokers with risk factors of COPD.