Open AccessGraphic analysis of FEV1 informative value when evaluating bronchodilating response in bronchial asthma patients
Author(s) -
S. S. Yartsev
Publication year - 2005
Publication title -
pulʹmonologiâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.126
H-Index - 6
eISSN - 2541-9617
pISSN - 0869-0189
DOI - 10.18093/0869-0189-2005-0-1-42-47
Subject(s) - bronchodilation , asthma , medicine , predictive value , reliability (semiconductor) , bronchodilator , power (physics) , physics , quantum mechanics
This work was aimed to graphic analysis of informative reliability of FEV 1 in the bronchodilation test assessed as the ratio to baseline or predictive values and to determine the optimal FEV 1 cut-off in bronchial asthma (BA) patients. The study analyzed 529 bronchodilation test results in 365 BA patients. A control group included 48 persons. The FEV 1 changes were calculated twice in each test: as ratios to the baseline and predictive values. A high diagnostic reliability of FEV 1 in the bronchodilation test as a percentage of baseline and predictive values was found in BA patients with baseline ventilation disorders using the ROC method. The informative reliability of the FEV 1%pred. was worse. Graphic analysis of cut-off for FEV 1 improvement made to distinguish positive or negative bronchodilation test results showed 10 % increase independently on the method. We propose the differentiated assessment of the bronchodilation test results using 10 % to 12 % cut-off depending on severity of ventilation disorders.