Open AccessMicroRNAs as Biomarkers of Cardiovascular Diseases
Author(s) -
В. В. Ромакина,
И. В. Жиров,
Svetla. Nasonova,
A V Zaseeva,
А. Г. Кочетов,
О В Лянг,
S. N. Tereshchenko
Publication year - 2018
Publication title -
kardiologiâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.159
H-Index - 16
eISSN - 2412-5660
pISSN - 0022-9040
DOI - 10.18087/cardio.2018.1.10083
Subject(s) - microrna , disease , pathogenesis , computational biology , expression (computer science) , bioinformatics , biology , medicine , gene , pathology , immunology , genetics , computer science , programming language
The fact that microRNAs play an important role in the development and pathogenesis of cardiovascular disease is beyond doubt. This article provides a brief overview of recent data that relate to microRNA expression in various cardiovascular diseases. Detecting significant changes in the level of expression of these molecules in various diseases means that microRNAs can be considered to be potential biomarkers of human pathologies including heart failure. Studying the relationship between the mechanisms of cardiovascular disease and the level of expression of a variety of microRNAs, as well as establishing their exact relationships with the genes is an urgent problem and requires further research.