Open AccessPostoperative assessment of malignant melanoma aggressiveness for further treatment personalization
Author(s) -
S. A. Yаrgunin,
Ya. N. Shoikhet,
А. Ф. Лазарев
Publication year - 2021
Publication title -
zlokačestvennye opuholi
Language(s) - English
Resource type - Journals
eISSN - 2587-6813
pISSN - 2224-5057
DOI - 10.18027/2224-5057-2021-11-1-45-51
Subject(s) - medicine , life expectancy , personalization , expectancy theory , melanoma , disease , oncology , scope (computer science) , stage (stratigraphy) , psychology , computer science , social psychology , population , paleontology , environmental health , cancer research , world wide web , biology , programming language
The aim of the study was to develop, implement and evaluate a method for predicting the aggressiveness of primary melanoma after surgical removal. It was established that the method for predicting tumor aggressiveness allows to determine the degree of aggressiveness, life expectancy, and to identify patients with poor prognosis in order to individualize treatment. The survival rate of patients was found to depend on the degree of aggressiveness of the tumor. A group of patients with stages 0-IIa (16,4 %) and tumor aggressiveness Grade II was identified as having a potentially high risk of progression, which can help individualize treatment for this category of patients. Using the method for predicting disease progression may potentially expand the scope of indications for further personalized treatment.