Open AccessROLE OF COPPER METAL AND BIOLOGICAL MARKERS IN PATIENTS WITH ENTEROBIASIS
Author(s) -
Esraa wathah,
Saleem Khteer Al-Hadraawy
Publication year - 2021
Publication title -
journal of experimental biology and agricultural sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.108
H-Index - 2
ISSN - 2320-8694
DOI - 10.18006/2021.9(5).657.662
Subject(s) - enterobius , immunoglobulin e , copper , medicine , immunology , gastroenterology , significant difference , chemistry , helminths , antibody , organic chemistry
The primary goal of this study was to determine the effect of copper in patients with Enterobius vermicularis infection, as well as its association with IgE and TRFC. The study was carried out with 583 suspected and thirty healthy respondents of the same age who visited the AL-Zahra maternity and pediatrics laboratory, AL-Hakeem hospital, in AL-Najaf province(Iraq) from July 2020 to June 2021. This study aimed to estimate the level of copper, IgE, and TRFC in patients suffering from enterobiasis. The concentration of three biomarkers (copper, IgE, and TRFC) in serum was determined using the ELISA technique as per the manufacturer's instructions while the concentration of copper was assessed by using the colourimetric method. Results of the study revealed that the concentrations of IgE and TRFC significantly increased (P≤0.05) in the blood sample of E. vermiculris infected patients, while the serum concentrations of copper decreased significantly (P≤0.05) compared to the control group. The results of the current study suggested that the E. vermicularis infection alters serum IgE and TRFC concentrations, which significantly impacts copper levels in the blood.