Design, Synthesis, Biophysical and Structure-Activity Properties of a Novel Dual MDM2 and MDMX Targeting Stapled α-Helical Peptide: ATSP-7041 Exhibits Potent In Vitro and In Vivo Efficacy in Xenograft Models of Human Cancer | Zendy

Vincent Guerlavais | Zendy; Krzysztof Darłak | Zendy; Bradford Graves | Zendy; Christian Tovar | Zendy; Kathryn Packman | Zendy; Karen A. Olson | Zendy; Kamala Kesavan | Zendy; Puja Gangurde | Zendy; James Horstick | Zendy; Aditi Mukherjee | Zendy; Theresa Baker | Zendy; X.E. Shi | Zendy; Silvia Lentini | Zendy; Ke Sun | Zendy; Sean Irwin | Zendy; Eric Feyfant | Zendy; Teng Teng To | Zendy; Zoran Filipovic | Zendy; C.A. Elkin | Zendy; Janice Pero | Zendy; S. Santiago | Zendy; T. Bruton | Zendy; Tomi K. Sawyer | Zendy; Allen Annis | Zendy; Nader Fotouhi | Zendy; Thomas J. Manning | Zendy; Huw M. Nash | Zendy; Lyubomir T. Vassilev | Zendy; Yong S. Chang | Zendy

Open Access

Design, Synthesis, Biophysical and Structure-Activity Properties of a Novel Dual MDM2 and MDMX Targeting Stapled α-Helical Peptide: ATSP-7041 Exhibits Potent In Vitro and In Vivo Efficacy in Xenograft Models of Human Cancer

Author(s) -

Vincent Guerlavais,

Krzysztof Darłak,

Bradford Graves,

Christian Tovar,

Kathryn Packman,

Karen A. Olson,

Kamala Kesavan,

Puja Gangurde,

James Horstick,

Aditi Mukherjee,

Theresa Baker,

X.E. Shi,

Silvia Lentini,

Ke Sun,

Sean Irwin,

Eric Feyfant,

Teng Teng To,

Zoran Filipovic,

C.A. Elkin,

Janice Pero,

S. Santiago,

T. Bruton,

Tomi K. Sawyer,

Allen Annis,

Nader Fotouhi,

Thomas J. Manning,

Huw M. Nash,

Lyubomir T. Vassilev,

Yong S. Chang

Publication year - 2013

Language(s) - English

Resource type - Conference proceedings

DOI - 10.17952/23aps.2013.184

Subject(s) - mdmx , in vivo , in vitro , peptide , chemistry , cancer research , dual (grammatical number) , mdm2 , pharmacology , biochemistry , medicine , biology , gene , art , microbiology and biotechnology , literature

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research