Open AccessToxicity Sub chronic Water Extract Meretrix meretrix Linnaeus In Vivo on Sprague dawley Rats
Author(s) -
Azwin Apriandi,
Kustiariyah Tarman,
Purwantiningsih Sugita
Publication year - 2016
Publication title -
jurnal pengolahan hasil perikanan indonesia
Language(s) - English
Resource type - Journals
eISSN - 2354-886X
pISSN - 2303-2111
DOI - 10.17844/jphpi.v19i2.13464
Subject(s) - in vivo , albumin , bilirubin , creatinine , urea , chemistry , zoology , medicine , endocrinology , biology , biochemistry , microbiology and biotechnology
Meretrix meretrix is one of the shells of sea water are widely utilized by people as food. This clam also has many properties and benefits, so in this study tested the effect of the water extract of Meretrix meretrix against blood chemistry profile Sprague Dawley rats with the method (OECD 413: 2009). Based on observations obtained growth, feed intake, weight of liver and kidney in normal conditions. Levels of urea, creatinine, cholesterol between the control mice treated with A/0.1 and A/1 were not significantly different (p> 0.05) while the levels of bilirubin and albumin between control mice treated with A/0.1 and A/1 results significantly different (p<0.05), but all blood chemistry parameters tested is still in the normal category.