Prospects for Local Application of Antiresorptive Drugs in Skeleton Bone Injuries and Diseases
Author(s) -
С. С. Родионова,
М. В. Лекишвили,
E. D. Sklyanchuk,
A. N. Torgashin,
A. Yu Ryabov,
Yu. B. Yurasova
Publication year - 2014
Publication title -
n n priorov journal of traumatology and orthopedics
Language(s) - English
Resource type - Journals
eISSN - 2658-6738
pISSN - 0869-8678
DOI - 10.17816/vto20140483-89
Subject(s) - medicine , bone remodeling , bone resorption , osteoporosis , dentistry , resorption , bisphosphonate , intervention (counseling) , psychiatry
Increase in bone tissue resorption intensity on the border “metal - bone” as a compulsory component of remodeling in systemic osteoporosis or other metabolic osteopathies may result in poor surgical treatment results. Present review is dedicated to the analysis of available data on the possibility of local bisphosphonates application for the depression of resorption process in the zone of surgical intervention. In some works it is noted that just the local use of bisphosphonates is more effective for the normalization of remodeling and provision of biologic stability of the implants.
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