Open AccessEndothelial dysfunction and aspectsof pharmacological correction in patientswith primary developed ischemic stroke
Author(s) -
Aleksandr Yuryevich Malygin,
А. Л. Хохлов
Publication year - 2013
Publication title -
obzory po kliničeskoj farmakologii i lekarstvennoj terapii
Language(s) - English
Resource type - Journals
eISSN - 2542-1875
pISSN - 1683-4100
DOI - 10.17816/rcf11139-45
Subject(s) - medicine , simvastatin , endothelial dysfunction , stroke (engine) , neuroprotection , ischemic stroke , cardiology , disease , ischemia , neurological deficit , medical prescription , anesthesia , pharmacology , mechanical engineering , engineering
The aim of the paper was to assess mortality, frequency of repeated cardiovascular events, neurological deficit dynamics and endothelial dysfunction in patients with primary determined ischemic stroke after treatment with simvastatin 40 mg in acute period of disease. Prescription of simvastatin 40 mg to patients in acute period of ischemic stroke accompanied by neuroprotective and antihypertensive therapy decreased a number of repeated cardiovascular events, positive dynamics of neurological status and regress of endothelial dysfunction appearance.