SIGNIFICANCE OF CONNECTIVE TISSUE DYSPLASIA IN DUODENAL ARTERIOMESENTERIAL COMPRESSION ORIGIN

Aim. To study the morphological changes in the duodenum in case of its arteriomesenterial compression and estimate their interaction with connective tissue dysplasia. Materials and methods. 70 patients (mean age 29.3 ± 2.6 years) with arteriomesenterial compression of the duodenum underwent morphological study of its wall and correlation analysis with histological changes in biopsy material of the skin. Results. Significant correlation of morphological indices of stromal-glandular changes in the duodenal mucosa with the signs of destruction and reorganization of connective tissue in histological preparations of the skin were established. Conclusions. Duodenal arteriomesenterial compression is a disease, conditioned by patient’s constitution. Its course is determined by peculiar features of connective tissue dysplasia. Morphological changes in duodenal wall confirm atrophy, the degree of manifestation of which corresponds to the stage of disease and is a reliable criterion for choosing rational therapeutic tactics.