STUDY OF THE DOSE-DEPENDANT CARDIOPROTECTIVE EFFECTS OF MACROLIDES | Zendy

Е. С. Черноморцева | Zendy; T. G. Pokrovskaya | Zendy; E. B. Artushkova | Zendy; M. V. Pokrovskiy | Zendy; Vladimir V. Gureev | Zendy; Yu V Legkova | Zendy

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STUDY OF THE DOSE-DEPENDANT CARDIOPROTECTIVE EFFECTS OF MACROLIDES

Author(s) -

Е. С. Черноморцева,

T. G. Pokrovskaya,

E. B. Artushkova,

M. V. Pokrovskiy,

Vladimir V. Gureev,

Yu V Legkova

Publication year - 2009

Publication title -

i p pavlov russian medical biological herald

Language(s) - English

Resource type - Journals

eISSN - 2500-2546

pISSN - 0204-3475

DOI - 10.17816/pavlovj2016484-87

Subject(s) - ventricle , myocardial infarction , pharmacology , lethality , dose dependence , medicine , necrosis , chemistry , cardiology , toxicology , biology

In laboratory animals is carried out a study of the dose-dependant cardioprotective effects of the group of modern macrolides with the simulation of the coronaroocclusional myocardial infarction. The preparations being investigated effectively decrease lethality and decrease the zone of the necrosis of left ventricle after coronaroocclusion. The dose-dependant effects are expressed in groups of 14- and 15- member macrolides.

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