Open AccessEXPERIMENTAL BASIS OF CELL CARRIERS USING FOR DIRECTED TRANSPORT OF ANTIBIOTICS AND FLUOROQUINOLONE IN NON-OBSTRUCTIVE PYELONEPHRITIS
Author(s) -
А. И. Лазарев,
Г. В. Сипливый,
A. V. Kukureka,
Lyubov Evgenievna Siplivaya
Publication year - 2009
Publication title -
rossijskij mediko-biologičeskij vestnik imeni akademika i. p. pavlova/rossijskij mediko-biologičeskij vestnik imeni akademika i.p. pavlova
Language(s) - English
Resource type - Journals
eISSN - 2500-2546
pISSN - 0204-3475
DOI - 10.17816/pavlovj2016478-83
Subject(s) - antibiotics , aminoglycoside , excretory system , medicine , pharmacology , microbiology and biotechnology , biology
It was shown in investigations on rats that introduction of aminoglycoside antibiotics or fluoroquinolone, included into erythrocyte or leukocyte carriers in pyelonephritis, decreased amount of leukocyte accumulation centers in kidneys increased or normalized the level of enzymes in the organ, excretory function of kidneys, impaired immunometabolic parameters.