Open AccessOur experience of bromfenac-containing NSAID use in patients after cataract surgery
Author(s) -
Yuriy I. Pirogov,
Пирогов Юрий Иванович,
Galina M Butina,
Бутина Галина Михайловна,
Roman A Morozov,
Морозов Роман Александрович,
Aleksandr A Oksentyuk,
Оксентюк Александр Анатольевич,
Mar’yana V Rybina,
Рыбина Марьяна Валериевна,
Madina R Chshieva,
Чшиева Мадина Руслановна,
Mikhail S Shatalov,
Шаталов Михаил Сергеевич
Publication year - 2016
Publication title -
oftalʹmologičeskie vedomosti
Language(s) - English
Resource type - Journals
eISSN - 2412-5423
pISSN - 1998-7102
DOI - 10.17816/ov9253-56
Subject(s) - medicine , dexamethasone , levofloxacin , phacoemulsification , macular edema , perioperative , cataract surgery , ophthalmology , anesthesia , surgery , intraocular lens , eye drop , antibiotics , visual acuity , microbiology and biotechnology , biology
Postoperative cystoid macular edema is an autoimmune reaction due to the blood-retinal barrier breakdown occurring at anterior segment inflammation. Aim: To analyze the effectiveness of various anti-inflammatory therapeutic schemes used in cataract surgery. Materials and methods. Phacoemulsification using similar consumables had been performed in 792 patients (932 eyes). They were divided into three groups: 1st group included patients receiving 1 to 3 dexamethasone (0.3 ml) and mesatone (0.1 ml) injections and Tobradex eye drops starting with 5 times a day for 4-5 weeks and then tapering (356 eyes); 2nd group (331 eyes) used eye drops of levofloxacin 0.5% solution and dexamethasone; and the 3rd group (325 eyes) in which instillations of ofloxacine and dexamethasone were combined with 0.09% eye drops solution of bromfenac (Broxinac) eye drops, the latter being prescribed QD for 2 days before and 16 days after surgery. Results. Treatment outcomes were less favorable in Group 1 (complications found in 15.2% of patients). Perioperative antibiotic eye drops of 0.5% levofloxacin solution provide a high level prevention of bacterial infection prevention after phacoemulsification. Patients treated with a combination of dexamethasone 0.1% solution eye drops and non-steroidal drug Broxinac had the lowest rate of postoperative inflammatory complications (7.0%).