Open AccessCell membrane state in schizophrenic patients
Author(s) -
A. A. Oslopova,
А. М. Карпов,
В. Н. Ослопов
Publication year - 2003
Publication title -
nevrologičeskij vestnik
Language(s) - English
Resource type - Journals
eISSN - 2304-3067
pISSN - 1027-4898
DOI - 10.17816/nb89662
Subject(s) - pathognomonic , schizophrenia (object oriented programming) , medicine , psychosis , endocrinology , psychology , psychiatry , disease
When investigating 216 schizophrenic patients a significant difference has been revealed in oscillation amplitude in absolute values of Na+Li+ countertransport at a period of time (speed variability of Na+Li+ countertransport), and having value s equal to 73,5, though in healthy people and people with different somatic diseases (even with bipolar disturbance) this variability is 13,515,7. Na+Li+ countertransport variability had not been changed because of the therapy, being present at the same level in schizophrenic patients both in acute periods and in the periods of remission. Discovered 5-fold increase of cell membrane permeability in Na+Li+ countertransport is probably aspecific (pathognomonic) sigh of schizophrenia.