Open AccessNew ways of immunodiagnosis in neurology
Author(s) -
А А Быкова,
А А Быкова,
Е. V. Volodina,
Е. V. Volodina,
Е. F. Olkhovskaya,
Е Ф Ольховская,
А. А. Шутов,
А. А. Шутов
Publication year - 1997
Publication title -
nevrologičeskij vestnik
Language(s) - English
Resource type - Journals
eISSN - 2304-3067
pISSN - 1027-4898
DOI - 10.17816/nb80165
Subject(s) - neostigmine , acetylcholine , myasthenia gravis , medicine , neurology , multiple sclerosis , immune system , mediator , balance (ability) , immunology , neuroscience , anesthesia , psychology , physical therapy , psychiatry
On the basis of immunological study of 65 patients with multiple sclerosis and 37 patients with myastenia the laboratory ways were offered for diagnosis of these diseases. For immunodiagnosis of multiple sclerosis a peroral rezerpine test was performed, based on the patients blood deficiency of serotonin and absence of immune system reaction on introducing agents, altering the balance of this mediator. For diagnosis of myasthenia acetylcholine test and immune variant of neostigmine methylsulfate test are offered, which are based on registration of altering of balance of endogenous acetylcholine in the patients blood under the enfluence of introducing neostigmine methylsulfate.