Open AccessUsage of neurospecific peptide substance “semax” in acute period of ischemic insult
Author(s) -
Eugene Gusev,
Veronica I. Skvortsova,
Е. J. Zhuravleva,
А.В. Ваничкин
Publication year - 1997
Publication title -
nevrologičeskij vestnik
Language(s) - English
Resource type - Journals
eISSN - 2304-3067
pISSN - 1027-4898
DOI - 10.17816/nb80150
Subject(s) - cerebrolysin , insult , medicine , anesthesia , electroencephalography , neuroprotection , psychiatry , philosophy , linguistics
In 30 patients being in acute period of hemispheric ischemic insult, investigation of medicinal substance Semax (synthetic analogue ACTH 4-10) was performed. Control group was made up of 80 patients with analogous in severty and localization of ischemic insult lesions, who received only unified therapy; the comparison group was made up of patients, receiving cerebrolysin and cronassial. 3 clinical scales of evaluation in points were used, as well as neurophysiologic control, uncluding EEG with toposelective Cartogram EEG, repeated investigation of somatosensoric induced potentials of brain with their charting. It was established that inclusion of Semax into intensive therapy complex for acute hemispheric ischemic insult reliably enfluences the rates of disturbed neurologic functions restoration, speeding regress of brain and focal disorders, especially motor disorders.