To the question of study of epileptogenic role of kynurenine in the epileptic pathogenesis (clinical and biochemical study) | Zendy

С. А. Громов | Zendy; I. P. Lapin | Zendy; Е. А. Fedotenkova | Zendy

Open Access

To the question of study of epileptogenic role of kynurenine in the epileptic pathogenesis (clinical and biochemical study)

Author(s) -

С. А. Громов,

I. P. Lapin,

Е. А. Fedotenkova

Publication year - 1997

Publication title -

neurology bulletin

Language(s) - English

Resource type - Journals

eISSN - 2304-3067

pISSN - 1027-4898

DOI - 10.17816/nb79874

Subject(s) - kynurenine , kynurenine pathway , pathogenesis , epilepsy , medicine , immunology , chemistry , tryptophan , psychiatry , biochemistry , amino acid

It was studied the content of endogenic convulsive agent, kynurenine, in the blood and liquor of 57 epileptic patients. It was revealed raising of kynurenine level in the blood of epileptic patients as compared with the level of control group, as well as more high level of kynurenine in the blood of patients with frequent seizures and lowering its level in liquor just after paroxysm. The abovesaid confirms the certain role of kynurenine in the pathogenesis of epilepsy.

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