Extrapyramidal disorders due to the intake of antipsychotics | Zendy

Z. A. Zalyalova | Zendy; Э. И. Богданов | Zendy

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Extrapyramidal disorders due to the intake of antipsychotics

Author(s) -

Z. A. Zalyalova,

Э. И. Богданов

Publication year - 2000

Publication title -

neurology bulletin

Language(s) - English

Resource type - Journals

eISSN - 2304-3067

pISSN - 1027-4898

DOI - 10.17816/nb79486

Subject(s) - akathisia , tardive dyskinesia , antipsychotic , parkinsonism , medicine , extrapyramidal symptoms , dyskinesia , psychiatry , extrapyramidal disorder , pediatrics , psychology , schizophrenia (object oriented programming) , disease , parkinson's disease

Among the side effects of taking antipsychotics, the leading place is occupied by extrapyramidal syndromes (ES) - akathisia, acute and tardive dyskinesia, parkinsonism, syndrome of the "leaning tower of Pisa", "rabbit", acute neuroleptic syndrome. The concept of a neuroleptic threshold assumes the simultaneous development of an antipsychotic effect and the emergence of an extrapyramidal syndrome. It has been proven that most antipsychotics have a limited therapeutic dose corridor, and ES caused by antipsychotics, which reduces the quality of life, occurs in 50-60% of cases and is the main reason for stopping treatment with these drugs [19].

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