Open AccessExtrapyramidal disorders due to the intake of antipsychotics
Author(s) -
Z. A. Zalyalova,
З. А. Залялова,
Э. И. Богданов,
Э. И. Богданов
Publication year - 2000
Publication title -
nevrologičeskij vestnik
Language(s) - English
Resource type - Journals
eISSN - 2304-3067
pISSN - 1027-4898
DOI - 10.17816/nb79486
Subject(s) - akathisia , tardive dyskinesia , antipsychotic , parkinsonism , medicine , extrapyramidal symptoms , dyskinesia , psychiatry , extrapyramidal disorder , pediatrics , psychology , schizophrenia (object oriented programming) , disease , parkinson's disease
Among the side effects of taking antipsychotics, the leading place is occupied by extrapyramidal syndromes (ES) - akathisia, acute and tardive dyskinesia, parkinsonism, syndrome of the "leaning tower of Pisa", "rabbit", acute neuroleptic syndrome. The concept of a neuroleptic threshold assumes the simultaneous development of an antipsychotic effect and the emergence of an extrapyramidal syndrome. It has been proven that most antipsychotics have a limited therapeutic dose corridor, and ES caused by antipsychotics, which reduces the quality of life, occurs in 50-60% of cases and is the main reason for stopping treatment with these drugs [19].