Open AccessCLINICAL AND NEUROLOGICAL CRITERIA FOR THE DIAGNOSISOF MYASTHENIA GRAVIS
Author(s) -
В Д Косачев,
С В Лобзин,
Т. М. Алексеева,
О А Крейс
Publication year - 2015
Publication title -
vestnik severo-zapadnogo gosudarstvennogo medicinskogo universiteta im. i.i. mečnikova
Language(s) - English
Resource type - Journals
eISSN - 2618-9704
pISSN - 2618-7116
DOI - 10.17816/mechnikov201573102-107
Subject(s) - myasthenia gravis , ptosis , medicine , weakness , neostigmine , thymectomy , neurology , lagophthalmos , pediatrics , surgery , eyelid , anesthesia , psychiatry
927 patients suffering from myasthenia gravis have been examined. A long-term follow-up analysis of the various forms of myasthenia in its clinical and neurological development has been conducted. Systematization and evaluation of the results have revealed major and frequent diagnostics criteria appropriate of myasthenia gravis. There are fatigable muscular weakness (92,3%), formula motor dis- turbances (91,9%), test with neostigmine (77,5%), generalized muscular weakness (76,3%), “flutter” and «migration» of the symptoms (71,1%), preservation of eye movements downward while it restricts in other directions (68,3%), combination ptosis and lagophthalmos on one side (50,1%). A diagram of clinical diagnostic, which help us to review a patient diagnosis of myasthenia gravis or suspect this exact disease has been developed.