Open AccessAPPLICATION OF CELLULAR TECHNOLOGIES FOR RESTORATIONOF PROCESS OF REGENERATION AT PEOPLE OF THE SENIOR AGE GROUPS
Author(s) -
A V Pechersky,
V I Pechersky,
A. B. Smolyaninov,
V N Velyaninov,
Ш Ф Адылов,
Владимир Семиглазов
Publication year - 2014
Publication title -
vestnik severo-zapadnogo gosudarstvennogo medicinskogo universiteta im. i.i. mečnikova
Language(s) - English
Resource type - Journals
eISSN - 2618-9704
pISSN - 2618-7116
DOI - 10.17816/mechnikov20146452-62
Subject(s) - regeneration (biology) , somatic cell , biology , stem cell , induced pluripotent stem cell , process (computing) , microbiology and biotechnology , peripheral blood mononuclear cell , physiology , immunology , computer science , genetics , in vitro , embryonic stem cell , gene , operating system
This manuscript is devoted to the vital topic - restoration of process of the regeneration at people of the senior age groups. Cells-predecessors and differentiated cells can divide a limited number of times and are not capable of providing regeneration of tissues during all of ontogenesis. The updating of tissues during such a long period is impossible without the participation of a specialized system responsible for regeneration. The given system is submitted by stem cells which are capable of being differentiated in all types of somatic cells and in a line of genital cells, and also have ability to self-update during the whole life of an organism. Results of research allow to consider, that the number of a pool of pluripotent stem cells at people of the senior age groups can be restored by a transfusion of mononuclear fraction of peripheral blood from young donors of 18-23 years of one blood types and a floor with the recipient (The patent of the Russian Federation № 2350340).