Open AccessExtracorporeal methods of detoxication in the complex treatment hepatitis
Author(s) -
F N Parfenchik,
A. Y. Kulidzhanov
Publication year - 2012
Publication title -
kazanskij medicinskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2587-9359
pISSN - 0368-4814
DOI - 10.17816/kmj2342
Subject(s) - medicine , detoxification (alternative medicine) , viral hepatitis , extracorporeal , ribavirin , plasmapheresis , hepatitis , hepatitis c , gastroenterology , viral load , hepatitis c virus , immunology , virus , pathology , antibody , alternative medicine
Aim. To study the effectiveness of extracorporeal methods of detoxification in the complex treatment of hepatitis’.Methods. Observed were 39 servicemen who received treatment for viral hepatitis’ A, B and C, at the age of 18 to 40 years (in 13 people - a severe form of viral hepatitis A, in 3 - a moderate form of hepatitis A, in 18 - severe form, and in 5 - moderate form of hepatitis B and C). Diagnostic criteria for chronic viral hepatitis’ include data of virological, clinical, laboratory and morphological studies. Percutaneous needle biopsy of the liver made it possible to make a diagnosis during chronic viral hepatitis based on a histological study, to monitor the effectiveness of treatment, to exclude congenital metabolic liver disease.Results. On the background of administration of the traditional scheme of treatment (regimen, diet, interferon therapy, detoxification, metabolic support, glucocorticosteroids, immune stimulants, antihistamines, bile acid absorbents, adsorbents, cholagogues drugs, hepatoprotectors), the average duration of treatment of viral hepatitis was 30-45 days. During the usage of extracorporeal methods of detoxification (plasmapheresis and hemosorption) the duration of treatment was significantly shorter.Conclusion. The usage of extracorporeal detoxification methods can shorten the treatment of viral hepatitis A, B and C.