Open AccessProblems and prospects of studying hemorrhagic fever with renal syndrome in the Republic of Tatarstan
Author(s) -
V. A. Boyko,
Бойко Владимир Андреевич,
T. A. Savitskaya,
Савицкая Татьяна Александровна,
Владимир Трифонов,
Трифонов Владимир Александрович,
И. В. Серова,
Серова Ирина Васильевна,
Г. Ш. Исаева,
Исаева Гузель Шавхатовна
Publication year - 2020
Publication title -
kazanskij medicinskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2587-9359
pISSN - 0368-4814
DOI - 10.17816/kmj2020-775
Subject(s) - epidemiology , disease , transmission (telecommunications) , medicine , natural history , puumala virus , virology , hantavirus , biology , environmental health , virus , pathology , electrical engineering , engineering
The paper presents the history of the study of hemorrhagic fever with renal syndrome (HFRS) at the Kazan Research Institute of Epidemiology and Microbiology from the beginning of the 50s to the present. The accumulated information allows to draw up general conceptions about the main source of infection, the biological structure of natural foci of infection, nosoarea and the main clinical forms of the disease, the nature and seasonality of the disease, the sex and age composition of patients, and the types of natural foci of HFRS. The stages of improving the methods of laboratory diagnosis of HFRS, development of a specific immunoglobulin against the serum of the Puumala virus are described. A significant contribution to the study of HFRS was the landscape-epidemiological ranking of the territory of the Republic of Tatarstan and the Middle Volga endemic for HFRS, with the identification of zones of special risk of human infection and the main factors that form them. At present, a reference center for monitoring HFRS has been created based on the Kazan Research Institute of Epidemiology and Microbiology, and the study of the properties of HFRS pathogens at the current molecular-genetic level continues.