Open AccessLung surfactants in acute pneumonia
Author(s) -
N. I. Guseva,
А. В. Некрасов
Publication year - 1988
Publication title -
kazanskij medicinskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2587-9359
pISSN - 0368-4814
DOI - 10.17816/kazmj99762
Subject(s) - pulmonary surfactant , phosphatidylcholine , lung , chemistry , permeability (electromagnetism) , chemical engineering , chromatography , phospholipid , materials science , biophysics , medicine , biochemistry , biology , membrane , engineering
Lung surfactant system, according to modern views, is a multicomponent, complex, self-regulating system, in which there are 3 main components: the surfactant itself - a thin lipoproteid film located at the air-liquid interface, hypophase and a cellular component represented by alveolocytes of types I, II, III. Lung surfactant system provides stability of alveoli during breathing, supports normal permeability of aerohematic barrier, participates in regulation of water balance, and has a protective function. Surface-active components of surfactant system are phospholipids, and more precisely their fraction - phosphatidylcholine.