Open AccessThe state of antitumor resistance in uterine myoma patients
Author(s) -
S. I. Zudikova
Publication year - 1988
Publication title -
kazanskij medicinskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2587-9359
pISSN - 0368-4814
DOI - 10.17816/kazmj99703
Subject(s) - endocrinology , medicine , excretion , immune system , peripheral blood , dexamethasone , immunology , pharmacology
We studied the state of antitumor resistance in patients with uterine myoma. Specific immune defense was assessed by the relative and absolute numbers of T-lymphocytes in peripheral blood, the ratio of subpopulations of T-helpers, T-helpers and T-suppressors, delayed-type hypersensitivity reactions with 2,4-dinitrochlorobenzene (DNCHB) and inhibition of leukocyte migration. Non-specific resistance was investigated by the activity of complement and its third fraction, as well as daily excretion of 17-OX. In order to clarify the state of the pituitary-adrenal system, dexamethasone suppression test was performed by determining the excretion of 17-OX after a two-day administration of the drug at a dose of 0.125 mg 4 times a day.