The state of antitumor resistance in uterine myoma patients | Zendy

S. I. Zudikova | Zendy

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The state of antitumor resistance in uterine myoma patients

Author(s) -

S. I. Zudikova

Publication year - 1988

Publication title -

kazan medical journal

Language(s) - English

Resource type - Journals

eISSN - 2587-9359

pISSN - 0368-4814

DOI - 10.17816/kazmj99703

Subject(s) - endocrinology , medicine , excretion , immune system , peripheral blood , dexamethasone , immunology , pharmacology

We studied the state of antitumor resistance in patients with uterine myoma. Specific immune defense was assessed by the relative and absolute numbers of T-lymphocytes in peripheral blood, the ratio of subpopulations of T-helpers, T-helpers and T-suppressors, delayed-type hypersensitivity reactions with 2,4-dinitrochlorobenzene (DNCHB) and inhibition of leukocyte migration. Non-specific resistance was investigated by the activity of complement and its third fraction, as well as daily excretion of 17-OX. In order to clarify the state of the pituitary-adrenal system, dexamethasone suppression test was performed by determining the excretion of 17-OX after a two-day administration of the drug at a dose of 0.125 mg 4 times a day.

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