Open AccessBiochemical and functional features of blood plates in myeloproliferative diseases
Author(s) -
В. А. Егорова,
O. E. Belyazo,
Э Г Щербакова,
М Н Блинов,
З Д Федорова
Publication year - 1988
Publication title -
kazanskij medicinskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2587-9359
pISSN - 0368-4814
DOI - 10.17816/kazmj98441
Subject(s) - myelofibrosis , platelet , medicine , sialic acid , hemostasis , platelet adhesiveness , myeloproliferative disorders , platelet aggregation , biochemistry , chemistry , bone marrow
The aim of this work was to study the relationship between changes in blood platelet sialic acid levels and adenine nucleotide pool regulation with the parameters of platelet hemostasis (adhesive-aggregation and retractile capacity of blood plates) in chronic myeloleukemia and idiopathic myelofibrosis. The studies were performed on platelets of healthy subjects (20), patients with chronic myeloleukemia (14) and idiopathic myelofibrosis (11) with advanced clinical manifestations.