Open AccessExperimental and clinical substantiation of the use of xymedon as an antioxidant in the complex treatment of patients with chronic osteomyelitis
Author(s) -
K. V. Malyshev
Publication year - 2022
Publication title -
kazanskij medicinskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2587-9359
pISSN - 0368-4814
DOI - 10.17816/kazmj96224
Subject(s) - antioxidant , osteomyelitis , medicine , peroxide , surgery , chemistry , biochemistry , organic chemistry
The antioxidant activity of blood plasma is studied in patients with chronic osteomyelitis. The experimental data on the effect of antioxidants of xymedone and methyluracil on the basic free radicals, peroxide oxidation of li poids and chemoluminescence of peritoneal macrophages of rats made it possible to justify the use of drugs in the complex treatment of patients in pre- and postoperative period. As a result of the use of xymedone in the complex treatment the blood indices improved, antioxidant plasma activity increased in 25 patients of the basic group. In patients of the control group taking methyluracil the efficiency of the treatment was less significant