Open AccessThe use of xymedon in surgical practice to increase the body's nonspecific resistance to infection
Author(s) -
S. G. Izmailov,
О. Д. Зинкевич
Publication year - 2022
Publication title -
kazanskij medicinskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2587-9359
pISSN - 0368-4814
DOI - 10.17816/kazmj96223
Subject(s) - organism , fibronectin , medicine , acute appendicitis , immunology , microbiology and biotechnology , biology , surgery , biochemistry , paleontology , extracellular matrix
Two groups of patients with various forms of acute appendicitis taking a drug of pyrimidine series, xymedone (102 patients) and methyluracil (138 patients) are examined. Nonspecific resistance of the organism to infection is estimated by the results of determining the functional activity of blood neutrophils, concentration of bioactive and immunoreactive fibronectin in blood plasma, activity of the fibrinostabilizing blood factor (factor XIII). Xymedone increases nonspecific resistance of the organism to infection by strengthening the functional activity of neutrophils, their reserve potentials. The use of xymedone in clinical surgery for increasing nonspecific resistance of the organism to infection is advisable.