Open AccessPathogenetic rationale for the use of cobalt-containing drugs in the treatment of anemia
Author(s) -
R. Kh. Khafiz’yanova,
L. N. Zalyalyutdinova,
N. E. Bakirova,
G. N. Murzagaleeva
Publication year - 2022
Publication title -
kazanskij medicinskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2587-9359
pISSN - 0368-4814
DOI - 10.17816/kazmj96181
Subject(s) - erythropoiesis , anemia , ineffective erythropoiesis , medicine , hemoglobin , pathological , physiology , immunology
Anemia is a clinical and hematological syndrome, which is understood as a decrease in the number of erythrocytes and / or hemoglobin. It accompanies many pathological processes and worsens the quality of life of patients. Anemia affects about 20% of men, 35% of women and 40% of children in the world [37]. Due to the imbalance in the erythron system, anemias are divided into three main groups: dyserythropoietic (erythropoiesis disturbance), hemolytic (increased destruction of erythrocytes) and hemorrhagic [18]. A separate group is made up of iron, B12-, folic- and protein-deficient anemias that occur when there is a lack of building material for the formation of erythrocytes