Open AccessIndicators of bone metabolism and bone mineral density in workers of a metallurgical plant
Author(s) -
A. F. Verbova
Publication year - 2022
Publication title -
kazanskij medicinskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2587-9359
pISSN - 0368-4814
DOI - 10.17816/kazmj96166
Subject(s) - bone mineral , bone remodeling , osteoporosis , osteocalcin , bone tissue , medicine , calcium , endocrinology , bone density , metallurgy , chemistry , alkaline phosphatase , biochemistry , materials science , anatomy , enzyme
The mineral density of bone tissue and phosphorus and calcium metabolism are studied by ultrasound densitometry of the calcaneus using the apparatus Achilles+ (Lunar, USA) in 99 men working in foundry of the metallurgical alluminium works. The control group consisted of 87 healthy men of similar age. The prolonged effect of aerosols of aluminium, lead, nickel, chromium, manganese, copper is accompanied by more frequent decrease the mineral density of bone tissue, increase of incidence of osteoporosis. Workers of aluminium production are characterised by hyperphosphatemia and hyperphosphaturia resulting in insignificant decrease of parathyroid hormone secretion. The normal level of osteocalcin, alcaline phosphatase in the decreased mineral density of bone tissue shows oppression of the bone-formation process in workers.