Relationship of immunomorphological reactions in the tumor stroma and regional lymph nodes in cancer

Regional lymph nodes play an important role in anti-tumor protection, and changes in them have prognostic value. However, the barrier function of lymph nodes is not always sufficient to hold back and destroy malignant cells. And if in some cases the latter, getting into the lymph nodes, are subjected to destruction, in others - they reproduce unhindered, which leads to further spread of the tumor process.