Open AccessGastric juice proteolytic activity in patients with acute dysentery
Author(s) -
A. G. Eliseev
Publication year - 1987
Publication title -
kazanskij medicinskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2587-9359
pISSN - 0368-4814
DOI - 10.17816/kazmj96078
Subject(s) - pepsin , proteolysis , histamine , dysentery , gastroenterology , proteases , proteolytic enzymes , medicine , concomitant , chemistry , biochemistry , enzyme , pathology
75 patients with acute dysentery Flexner's disease without concomitant and past diseases of the digestive organs were examined. The clinical diagnosis was confirmed bacteriologically.The aim of the work was to study the total proteolytic activity of the gastric juice by Ensky and Mirsky method, which allows to evaluate proteolysis in a wide pH range at its values from 1.5 to 7.0, including optimums of pepsin, gastrixin and, probably, other gastric proteases. Studies were performed before histamine administration (0.1 mg per 10 kg weight) and thereafter.