Open AccessThe nervous system as a source of antibody production in relapsing typhus. Plant (Wien. kl. Woch., 1928, No. 28)
Author(s) -
Andrea Weinstein
Publication year - 1928
Publication title -
kazanskij medicinskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2587-9359
pISSN - 0368-4814
DOI - 10.17816/kazmj91162
Subject(s) - antibody , nervous system , antigen , immunology , irritation , membrane , blood–brain barrier , medicine , chemistry , central nervous system , biology , neuroscience , biochemistry
The generally accepted position that the hemato-encephalic barrier serves as an obstacle for the penetration of antibodies from blood into liquor is true only when the cerebral membranes are unaffected; in acute infections (e.g., artificial recurrence) with irritation of the cerebral membranes the barrier passability of antibodies increases dramatically. In addition, a number of carefully conducted experiments Plant'y managed to prove that by direct introduction of antigen into liquor (for example, by introducing rabbit red blood cells of ram into liquor) in the latter it is possible to cause appearance of antibodies, and thus the nervous system should be looked at as a possible source of production of the latter.