About the pathogenesis of osteoporosis

The main problem of metabolic bone diseases is osteoporosis, a dystrophic bone disease characterized by its low mass, impaired bone tissue microarchitectonics and a high risk of fractures [11]. According to statistics, half of women in menopause are affected by this disease, every second is over 70 years old, and by 2020 the number of patients with osteoporosis will double [12]. After a hip fracture with osteoporosis, mortality in the first year is 20%, and the cost of treatment is estimated at millions of rubles; 85% of patients remain disabled, and rehabilitation requires at least 12 months [12].