Open AccessTreatment of patients with hemorrhagic erysipelas using natural inhibitors of proteolysis
Author(s) -
V. L. Cherkasov,
Т Д Большакова,
В. А. Кузнецов,
S. M. Mikerin,
S. Orazberdyev
Publication year - 1996
Publication title -
kazanskij medicinskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2587-9359
pISSN - 0368-4814
DOI - 10.17816/kazmj90950
Subject(s) - erysipelas , fibrinolysis , proteolysis , medicine , inflammation , gastroenterology , pathology , immunology , biology , enzyme , biochemistry
The clinical efficacy and effect on the processes of kininogenesis and fibrinolysis of natural inhibitors of proteolysis (hordox and contrical) in patients with hemorrhagic erysipelas are studied.The drugs are injected to the inflammation focus by electrophoresis. The normalization of characteristics of kallikrein-kinin system and fibrinolysis showing the activation of these systems in the period of hemorrhagic syndrome formation is established. The plausible decrease of the length of local acute manifestations of hemorrhagic erysipelas in correlation with clinically uniform comparison group data is revealed, the disease transformation into bullous and hemorrhagic form is unavailable. The erysipelas complications are noted three times more rarely than in comparison group.