Open AccessGlutathione reductase system and acetylcholinesterase activity of erythrocytes in ischemic heart disease
Author(s) -
V. N. Fatenkov,
N. A. Klenova,
E. I. Seleznev,
A. S. Stegunin,
R. A. Timerbulatov
Publication year - 1984
Publication title -
kazanskij medicinskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2587-9359
pISSN - 0368-4814
DOI - 10.17816/kazmj88727
Subject(s) - glutathione reductase , glutathione , acetylcholinesterase , hypoxia (environmental) , enzyme , homeostasis , biochemistry , chemistry , reductase , lactate dehydrogenase , dehydrogenase , pharmacology , medicine , endocrinology , biology , glutathione peroxidase , oxygen , organic chemistry
In the mechanism of hypoxia developing in ischemic heart disease (CHD), along with other factors, structural and functional disorders of the organization of erythrocytes are important [1, 8, 12]. The glutathione reductase system, including glucose-6-phosphate dehydrogenase (CF 1.1.1.49), glutathione reductase (CF 1.6.4.2) and reduced glutathione, plays a certain role in maintaining erythrocyte homeostasis (ER) [15]. The experiment shows the relationship of these systems with the activity of membrane-bound enzymes and, in particular, with acetylcholinesterase (CF. 3.1.1.7.) [4].