Issues of regulation of physiological functions in allergy

Allergic restructuring of the body is accompanied not only by disorders on the part of individual organs and systems, but also by a change in the nature of regulatory processes, which determines a different level of functioning of the body as a whole. The successes of immunology, especially in recent years, have given a new incentive to clarify the patterns of immunological processes with altered reactivity of the body, in particular with allergies. However, the process of allergization cannot be considered only in terms of immunological shifts, as is sometimes done, since the immunological aspect is only one of the sides of the complex problem of allergic reactivity of the body. According to Ado (1952), a significant role in the development of allergy belongs to the pathophysiological mechanisms of immunity due to the effect of antigens on the neuro-reflex regulation of functions outside of direct connection with the production of antibodies or phagocytosis.