Open AccessDifferential diagnosis of various forms of rickets
Author(s) -
N. N. Arkhipova,
S. V. Maltsev,
В. Б. Спиричев,
Н. Д. Фанченко,
O. A. Pereverzeva
Publication year - 1983
Publication title -
kazanskij medicinskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2587-9359
pISSN - 0368-4814
DOI - 10.17816/kazmj87885
Subject(s) - rickets , hormone , endocrinology , calcium , vitamin d and neurology , pathogenesis , medicine , mineralization (soil science) , tetany , redistribution (election) , chemistry , organic chemistry , nitrogen , politics , political science , law
The issues of etiology and pathogenesis of rickets are currently being largely revised. The basis for this is new data on the metabolism of vitamin D, the provision of healthy and sick children with various forms of rickets. Vitamin D is a precursor to at least three hormones that regulate the absorption of calcium and phosphates in the intestine and bone mineralization. The endogenous formation of vitamin D3 in the skin, its humoral redistribution to the liver and kidneys, in which its chemical modification takes place, the fixation of metabolites in the intestine, kidneys, bones and muscle by specific receptors, and, finally, the control of its transformation according to the feedback principle all this is characteristic of hormonal compounds [6].