About hemolytic anemia Markiafava - Micheli

Chronic hemolytic anemia with predominantly intravascular hemolysis was described as early as 1908 by Chaoferard and Troisier (2 cases). In 1911 Markiafava identified this disease as a peculiar form of anemia, and in 1928 Micheli gave a detailed description of the disease. In the domestic literature, individual diseases of this kind have been described more than once. Since the pathogenesis and therapy of this disease remain unclear, the description of the clinic and therapy of even isolated cases deserves publication.