Open AccessToxic epidermal necrolysis (Lyell's syndrome)
Author(s) -
V. A. Michurin
Publication year - 1981
Publication title -
kazanskij medicinskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2587-9359
pISSN - 0368-4814
DOI - 10.17816/kazmj84491
Subject(s) - toxic epidermal necrolysis , medicine , dermatology , disease , tetanus , toxoid , measles , antibiotics , pediatrics , intensive care medicine , immunology , vaccination , pathology , microbiology and biotechnology , biology
In recent years, descriptions of cases of toxic epidermal necrolysis - Lyell's syndrome in children - have increasingly appeared in the periodical literature. Most authors consider this disease as a toxic-allergic reaction to various medicinal substances: antibiotics, sulfa drugs, etc. Cases of Lyell's syndrome in children after administration of measles and tetanus toxoid are described. The prognosis of the disease is difficult: 30% are fatal. Patients die from toxicosis at the height of the disease or from septic complications.