Open AccessHypogammaglobulinemia and therapeutic use of gamma globulin
Author(s) -
Abukova Ra
Publication year - 2021
Publication title -
kazanskij medicinskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2587-9359
pISSN - 0368-4814
DOI - 10.17816/kazmj84095
Subject(s) - gamma globulin , hypogammaglobulinemia , measles , smallpox , medicine , poliomyelitis , immunology , whooping cough , virology , antibody , vaccination , pediatrics
In the Soviet Union, gammaglobulin was first obtained in 1946 by Kholchev and Kolesnikova from the blood serum of donors. At first, it was used to prevent measles, and then, as the content of various antibodies in it was studied, it began to be used for poliomyelitis (Leitman, Strakhova, Denisenko, Bogdanov), Botkin's disease (Ananiev, Grachev, Fabrikantov), whooping cough (Khropetskaya), scarlet fever ( Kaushanskaya, Zhagullo, Mauerman). Gammaglobulins were also obtained from the blood serum of animals, which were successfully used for rabies (Selimov, Durasova, Kovalevskaya. Kobrinsky, Chun-syun), plague (Semenova, Ponomareva), smallpox (Mirosennikova). Gammaglobulin in industrial conditions is prepared from the placental serum of healthy women in labor.